Unlock a rare development opportunity in the heart of Potrero Hill with this vacant duplex at 2109-2111 22nd Street. Perfectly positioned in one of San Francisco’s most coveted neighborhoods, this property features two charming "mini-residences" offering immediate versatility: a light-filled top-floor unit with a private deck and a lower-level retreat leading to an expansive patio. Situated on a deep lot, the site serves as a blank canvas for a visionary expansion or a lush urban garden sanctuary.
The location is a commuter’s dream with seamless freeway access and close proximity to Zuckerberg San Francisco General, UCSF Mission Bay, and the convenience of Whole Foods just blocks away.
Add this duplex to your portfolio and take advantage of the city’s current red hot rental market, or develop the property to maximize its potential in one of San Francisco’s coolest neighborhoods, Potrero Hill.
| Location | |
| Subdivision | - |
| County | San Francisco County |
| Elementary School | - |
| Middle School | - |
| High School | - |
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MLS number: 41134522
Listing agent:
Herman Chan
Listing broker:
Golden Gate Sotheby's International Realty
(510) 542-2600
Last update: Monday, June 29 2026 at 1:27 p.m. EDT
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